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D-Pantethine

  • CAS No.:16816-67-4
  • Molecular Formula:C22H42N4O8S2
  • Molecular Weight:554.729
  • 98% Liquid by HPLC, JP16
  • 50% Powder by HPLC

    Feature

    D Pantethine is a more stable and active form of pantothenic acid (vitamin B5). It is also a precursor of coenzyme A (CoA) in the body.
    It is known for its beneficial effects on metabolism, energy production, and lipid metabolism.
    Pantethine is often used as a supplement ingredient to support heart health and metabolic function.
    It is more effective than regular pantothenic acid because it has a higher bioavailability and is more easily absorbed.

    Specification-COA

    98% Liquid

    ANALYSISSPECIFICATIONRESULTS
    AppearanceClear, colorless to pale yellow viscous liquidClear, colorless viscous liquid
    SolubilityMiscible with water, with methanol and with ethanol(95%)Miscible with water, with methanol and with ethanol(95%)
    Optical rotation+15.0°~+18.0°+15.9°
    IdentificationA, B, C, D should be positivePositive
    Water18.0%~22.0%。20.44%
    Residue on Ignition≤0.1%0.05%
    Heavy metals≤10ppm<10ppm
    Arsenic≤1ppm<1ppm
    Related substances·D-Pantothenic Acid ≤0.1%0.02%
    ·Impurity A ≤0.3%0.16%
    ·Impurity B ≤0.5%0.08%
    ·Unknown impurities ≤0.1%0.04%
    ·Total impurities ≤1.0%0.41%
    Chiral isomers≤0.5%0.28%
    Mercapto compoundsA red color should not be developedA red color is not developed
    Residual solvents·Methanol ≤0.3%ND
    ·Ethanol ≤0.5%ND
    ·Isopropanol ≤0.5%ND
    ·Dichloromethane ≤0.06%ND
    Assay≥98.0% (on the dried substance)99.25%
    Bacterial Endotoxins·Bacteria amount  <1000cfμ/g;·Mildew and microzyme amount <100cfμ;·Escherichia coli  N.T.Conforms
    ConclusionThe substance Pantethine complies with the Requirements of In House Specifications.

    50% Powder

    ANALYSISSPECIFICATIONRESULTS
    AppearanceFine powder, good fluidityConforms
    ColorWhite to off-whiteConforms
    Assay48.0% - 52.0%50.9%
    Water≤4.0%3.0%
    Heavy metals(Pb)≤10ppmConforms
    Arsenic/CadmiumLead/Mercury≤1ppm(each one)Conforms
    Escherichia coli≤100 cfu/gNegative
    Staphylococcus aureusNegativeNegative
    SalmonellaNegativeNegative
    Mildew and microzyme amount ≤100 cfu/g< 10 cfu/g
    Microbe amount ≤1000 cfu/g< 10 cfu/g
    ConclusionThe substance Pantethine complies with the Requirements of In House Specifications.

    What does pantethine do for the body?

    1. It is beneficial to metabolism. Panthioethylamine is the active fragment of coenzyme A. It can serve as a reaction handle for key substances in lipid biochemical transformation.
    2. Pantethine is used in the synthesis of pesticides and other organic sulfur compounds.
      It has been studied for controlling dyslipidemia. It is beneficial for metabolic syndrome or abnormal blood lipids.
    3. Energy generation. It helps with energy metabolism and supports functions such as the Krebs cycle, thereby generating ATP.
    4. Support skin health. It can promote skin health and facilitate wound healing.

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