GHK-Cu powder, also known as Copper Tripeptide-1 and Copper Peptide, is a complex composed of copper ions and tripeptide-1. It is a small molecule protein with a blue appearance in both powder and aqueous solution.
Through precise proportions, copper peptides with specific biological activities can be produced. Copper Peptide Powder is commonly used in serums, creams, and other skin care and hair care products. Many well-known brands have developed products with blue copper peptide as the main active ingredient.
Other peptide products with anti-aging effect:
Acetyl Hexapeptide 8 Palmitoyl Tripeptide 1 AHK-CU
To incorporate GHK-Cu Powder into formulations effectively, here are key considerations and steps:
Water-Soluble: GHK-Cu Powder is water-soluble, so it should be dissolved in the aqueous phase of your formulation. It can be added directly into the water phase or any water-based ingredients such as hydrosols or toners.
Optimal Solubility: Ensure that the powder is fully dissolved to avoid any granules or sediment in the final product. It typically dissolves well in water when mixed at a concentration range of 0.1% to 1%, depending on the desired efficacy.
pH Range: GHK-Cu Powder is most stable and effective when the pH of the formulation is between 5.0 to 7.0. Formulations with a pH that is too high or low may affect the peptide’s stability.
Adjusting pH: If the formulation requires a different pH, consider adjusting the pH to the recommended range using mild pH adjusters.
During Cooling: GHK-Cu Powder should generally be added to the formulation after the formulation has been heated (if applicable) and cooled down to a temperature under 40°C (104°F). High temperatures can compromise the peptide structure.
Post-Emulsification: If making emulsions (creams, lotions), GHK-Cu Powder should be added after the emulsification process, during the cooling phase when the temperature is below 40°C, to maintain the integrity of the peptide.
Typical Range: GHK-Cu Powder is effective at concentrations from 0.1% to 1% in most formulations. Higher concentrations may be used in specialized products like serums aimed at intensive skin conditioning or anti-aging.
Optimization: The exact percentage can vary based on the specific product and desired skin benefits, so it’s important to test formulations to determine the optimal concentration for the intended use.
Synergistic Ingredients: GHK-Cu Powder works well in combination with other peptides, antioxidants (like Vitamin C), hyaluronic acid, and growth factors. These ingredients enhance its anti-aging, soothing, and skin conditioning effects.
Avoid Harsh Acids: Avoid combining GHK-Cu Powder with formulations containing strong acids (such as low pH Vitamin C or AHA formulas), as they can destabilize the peptide.
Mixing: When dissolving GHK-Cu Powder, use gentle stirring or agitation to prevent clumping. It should be mixed well to ensure even distribution throughout the formulation.
Water Phase First: If you're incorporating the powder into a complex formula, add it to the aqueous phase first, then mix in your other ingredients (emollients, oils, etc.).
Storage: Store the final product in airtight containers and keep it away from direct sunlight and extreme temperatures. GHK-Cu Powder should be stored in a cool, dry place to preserve its quality.
Avoid Oxidation: Since GHK-Cu Powder has antioxidant properties, ensure that your formulation remains sealed to prevent oxidation.
| Items | Specification | Results |
| Peptide purity (By HPLC) | ≥98.0% | 99.16% |
| Copper Content | 8-12% | 10.91% |
| GHK Content | 55-65% | 64.2% |
| Acetate Content | 30.0% | 19.62% |
| pH (1% water solution) | 6.0-8.0 | 6.93 |
| Appearance | Blue to purple powder | Conforms |
| Solubility | ≥100mg/ml(H2O) | Conforms |
| Impurity | 2.0% | 0.84% |
| Water Content (Karl Fischer) 8 | 8.0% | 3.87% |
| Identity by HPLC | The retention is the same with the reference substance | Conforms |
| Identity by MS | 401.91±1 | Conforms |
| Conclusion: | Conform to the standard |
GHK-Cu Powder is a multifunctional skincare ingredient that can be applied across various product categories, including but not limited to anti-aging, skin repair, brightening, soothing, and hair care. Its unique properties, such as supporting collagen synthesis, promoting cell renewal, and offering antioxidant benefits, make it an ideal ingredient for premium skincare products. It effectively enhances the performance of products and boosts market competitiveness.
Application Products: Anti-aging serums, creams, eye creams, anti-aging masks
Description: GHK-Cu Powder is widely used in anti-aging products due to its ability to support collagen production, enhance skin elasticity, and address signs of aging. It supports cell renewal, making it an ideal ingredient for combating fine lines, wrinkles, and loss of firmness.
Application Products: Repair serums, barrier support creams, post-blemish care.
Description: GHK-Cu Powder is renowned for its skin conditioning and restorative properties. It is especially effective in products aimed at barrier support, after-sun care, and improving skin texture. It supports skin recovery, helps soothe redness, and restores a healthy glow.
Application Products: Whitening serums, brightening creams, pigmentation treatments
Description: GHK-Cu Powder has strong antioxidant properties, helping to fight free radical damage and reduce the appearance of dark spots and uneven skin tone. It supports skin radiance, leading to a more even complexion.
Application Products: Sensitive skin serums, soothing creams, calming gels
Description: GHK-Cu Powder is known for its powerful soothing effects, helping to calm skin stressed by environmental factors or aging. It is perfect for sensitive skin products, providing comfort to irritation or redness.
Application Products: Day creams, SPF sunscreens, anti-pollution creams
Description: Thanks to its antioxidant and anti-aging properties, GHK-Cu Powder is an ideal ingredient for daytime skincare and protective products. It effectively neutralizes pollutants and environmental stressors.
Application Products: Scalp serums, volumizing shampoos, conditioners
Description: GHK-Cu Powder is not only beneficial for skin care but also plays a vital role in hair care. It revitalizes the scalp environment, promoting healthy-looking hair follicles, improving hair quality, and supporting hair density.
Application Products: Body lotions, hand creams, foot repair creams
Description: GHK-Cu Powder's nourishing properties make it an excellent addition to body care products. It helps relieve dry, rough skin and enhances smoothness and elasticity.
Application Products: Cleansers, exfoliating creams, deep cleansing masks
Description: GHK-Cu Powder can also be incorporated into cleansing products, supporting skin renewal. It helps improve the health of the skin's surface, removing impurities while encouraging a fresh appearance.
Application Products: Eye creams, eye serums, under-eye care
Description: GHK-Cu Powder can be added to eye care products to help reduce the appearance of fine lines, puffiness, and dark circles. It targets signs of aging and tightens the delicate skin around the eyes.
Application Products: Anti-aging masks, repair masks, brightening masks
Description: GHK-Cu Powder is well-suited for incorporation into mask formulations, where it can work synergistically with other conditioning ingredients to rapidly improve skin condition.
Application Products: Anti-pollution serums, purifying creams, cleansing sprays
Description: GHK-Cu Powder's antioxidant properties make it a preferred ingredient in anti-pollution skincare. It effectively helps protect the skin from environmental stressors.
Application Products: Sunscreens, daytime creams (with SPF)
Description: GHK-Cu Powder helps minimize environmental stress on the skin when included in sunscreen formulations, enhancing skin barrier function and providing additional anti-aging benefits.
GHK-Cu Powder is relatively stable in formulations when stored and used correctly. It remains most stable in products with a pH between 5.0 and 7.0 and should be added during the cooling phase of formulation (below 40°C) to prevent degradation. Exposure to high temperatures, UV light, and oxygen can compromise its stability, so it’s essential to store the powder and final product in airtight, light-resistant packaging in a cool, dry place. Additionally, it is recommended to avoid combining it with strong acidic ingredients (e.g., AHAs) to prevent destabilization. When handled properly, GHK-Cu Powder has a shelf life of 1 to 2 years.
Yes, GHK-Cu Powder can be used in combination with other active ingredients, but compatibility should be carefully considered. It works well with ingredients like hyaluronic acid, peptides, antioxidants (e.g., Vitamin C and E), and growth factors as they can complement its skin-conditioning and anti-aging effects. However, it should be avoided in formulations with strong acids (like AHAs or low pH Vitamin C) or highly alkaline ingredients, as they can destabilize the peptide. To ensure optimal results, it’s important to maintain a balanced pH (5.0–7.0).
The recommended usage concentration for GHK-Cu Powder typically ranges from 0.1% to 1% in formulations, depending on the desired effect and type of product. For general skincare products like serums, creams, and lotions, a concentration of 0.1% to 0.5% is usually effective for supporting collagen production and providing anti-aging benefits. For more intensive applications or targeted products (e.g., anti-aging serums or scalp care), higher concentrations, such as 0.5% to 1%, may be used. It’s essential to test the formulation to ensure the right balance between effectiveness and skin tolerance.
We offer a reliable and consistent supply of GHK-Cu Powder, ideal for large-scale production. Our products are of premium quality, ensuring optimal performance in your formulations. We provide customized procurement solutions tailored to your specific requirements, including flexible packaging and shipping options to meet diverse market demands.
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