Hexamidine Diisethionate salt is a water-soluble cationic substance. It is neutralized by an organic base (hexamidine) and an acid (hydroxyethylsulfonic acid).
| Tested Items | Specifications | Results |
| Appearance | White to off-white powder | White powder |
| IR | Should be consistent with that of the reference product | Complies |
| Qualitative Identification | Dissolve about 40 mg in 5 mL of water and add dropwise with shaking 1 mL of a 100 g/L solution of sodium chloride. Allow to stand for 5 min. An abundant,shimmering white precipitate is slowly formed. | Complies |
| HPLC | The retention time of the main peak of the test solution should be the same as that of the control solution | Complies |
| Loss on drying | ≤0.3% | 0.22% |
| Residue on ignition | ≤0.1% | 0.02% |
| Purity | ≥99.0% | 99.30% |
| Hexamidine content | 57.5-59.5% | 58.30% |
| Pb | ≤10mg/kg | ND |
| As | ≤2mg/kg | ND |
| Hg | ≤1mg/kg | ND |
| Cd | ≤5mg/kg | ND |
| Total bacterial cfu/g | ≤200cfu/g | <10 cfu/g |
| Molds and Yeast Count,cfu/g | ≤100cfu/g | <10 cfu/g |
| Thermotolerant Coliforms /g | Negative | ND |
| Staphylococcus aureus /g | Negative | ND |
| P.Aeruginosa /g | Negative | ND |
It is mild and non-irritating, and has the advantages of high-efficiency broad-spectrum antibacterial and bactericidal capabilities, and is widely used in personal care products. It has unique advantages in anti-dandruff, anti-acne and anti-odor formulations.
Topical preparations.
Preservatives in skin care and personal care products.
Betamethasone powder is one of the most widely used powerful corticosteroids.
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