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Hyaluronic Acid Sodium

  • CAS:9067-32-7
  • Appearance: White Powder
  • MF:C14H22NNaO11
  • Certification:ISO9001, US FDA Registration
  • Products can be customized
  • Cosmetic grade, pharmaceutical grade, food grade

    Feature

    Hyaluronic Acid Sodium(Sodium hyaluronate) is a glycosaminoglycan naturally present in the dermis. It is the sodium salt form of hyaluronic acid.
    It is a hydrophilic compound with a half-life of 1 to 2 days in its natural form.
    According to molecular weight, hyaluronic acid can be divided into high molecular weight, medium molecular weight and low molecular weight.
    Sodium hyaluronate is safe, it can be completely metabolized in the body, non-toxic and sterile.
    In short, it is widely used in dietary supplements, beauty, skin care and other products. In addition, some developed countries have approved sodium hyaluronate as a food additive.

    Type

    TypeMolecular weight range
    High molecular weight1800kDa~2000kDa
    2000kDa~2200kDa
    2200kDa~2500kDa
    Medium molecular weight800kDa~1000kDa
    1200kDa~1500kDa
    Low molecular weight20kDa~40kDa
    Sodium oligomeric hyaluronate≤10kDa

    Specification-COA

    Test ItemsSpecificationsResults
    IdentificationIR Identification orcomparable testComplies
    AppearanceWhite powderComplies
    Transparency (in 0.1%aq.sol.,)≥99.0%99.3%
    pH6.0~7.56.2
    Intrinsic viscosityActual value0.46dL/g
    Molecular weight≤10KDa9.62KDa
    Kinematic viscosityActual value1.01mm²/s
    Mesh≥80Complies
    Loss on drying≤10.0%3.7%
    Residue on ignition15.0~20.0%18.8%
    Heavy metals≤20ppm<20ppm
    Arsenic≤2ppm<2ppm
    Protein≤0.1%0.04%
    Assay≥93.0%95.7%
    Glucuronic acid≥45.0%46.3%
    Total bacterial count≤100CFU/g<100CFU/g
    Yeasts & mold≤100CFU/g<100CFU/g
    E. coliNegativeNegative
    StaphNegativeNegative
    Pseudomonas aeruginosaNegativeNegative
    SalmonellaNegativeNegative
    Conclusion:Meet the requirements

    Function

    1. First of all, it is an ideal moisturizing ingredient and is therefore used as a moisturizer in cosmetics. Hyaluronic acid is often used as an ideal natural moisturizing factor due to its own material properties.
    2. Its most well-known function is "injection beauty" for facial moisturizing and facial shaping.
      After hyaluronic acid is injected into the body, it can not only play a role in volume filling, but also stimulate collagen.
    3. It has a relieving effect on joint pain caused by periarthritis of the shoulder and rheumatoid arthritis.
      Sodium hyaluronate plays multiple roles, including:
      (1) Protecting chondrocytes and promoting their synthesis.
      (2) Anti-inflammatory, lubricating, and protective effects on articular cartilage.
      (3) Promoting endogenous HA secretion.
      (4) Analgesia.
      (5) It can reduce the degree of bone wear during exercise.
    4. In addition, the medicine grade can be used as an auxiliary drugs for ophthalmology surgery, which is also added to the eye drops. For dry eyes, corneal epithelium damage.

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