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Milk Thistle Extract Powder

  • OEM ODM AVAILABLE
  • CAS:84604-20-6
  • Formula :C25H22O10
  • Appearance:Yellow to Yellowish-Brown
  • Specification: silybin、isosilybim、silydianin 、silychristin
  • Certification: KOSHER,HALAL,GMP,ISO9001etc.

    Feature

    Milk Thistle Extract Powder contains a large amount of flavonoids in the whole plant. These flavonoids are collectively called silymarin.It is a mixture of two diastereoisomers, silybin A and silybin B.

    It is extracted from the dried seeds and fruits of the milk thistle plant by organic solvents. Its main components include silybin, isosilybim, silydianin and silychristin, among which silybin has the highest content and activity.
    The extract has a light yellow to brown appearance due to different content, insoluble in water, and easily soluble in methanol and ethanol.

    Application

    1.Milk thistle supplements or other health care products on the market.
    2.Preparations for various liver diseases.

    Specification-COA

    Test itemsSpecification Results
    AppearanceAmorphous PowderConforms
    ColourYellow to Yellowish-BrownConforms
    OdourSlight, SpecificConforms
    Solubility
    - in WaterPractically InsolubleConforms
    - in Methanol and AcetoneSolubleConforms
    Sulphated AshNMT 0.5%Conforms
    Heavy metalsNMT 10 PPMConforms
    Loss On Drying (2 Hours 105 ℃)NMT 5.0%2.8%
    Powder size
    Mesh 80NLT 90%Conforms
    Assay  of  Silymarin (Tested by UV&Calculated toreference to dried basis)NLT 80%82.4%
    Assay  of  Silymarin (Tested by HPLC&Calculated toreference to dried basis)NLT 40%42.0%
    -Silybin A.B. 25.2%
    -Isosilybin A.B. 5.0%
    -Silydianin&Silychristin 11.8%
    Residual Solvents
    - N-hexaneNMT 0.029%Conforms
    - MethanolNMT 0.3%Conforms
    -AcetoneNMT 0.5%Conforms
    - Ethyl AcetateNMT 0.5%Conforms
    - EthanolNMT 0.5%Conforms
    Microbiological Quality (Total viable aerobic count)
    - Total bacterial countNMT 1,000.0 CFU/gConforms
    - Moulds & YeastsNMT 100.0 CFU/gConforms
    - Escherichia coliNot detectedConforms
    - SalmonellaspeciesNot detectedConforms
    Guarantee of Non-Irradiation ---- Qualified

    Function

    Milk thistle extract has a wide range of pharmacological activities:

    1. On the one hand, silymarin is widely used as a liver protection ingredient in various liver diseases. It has a good therapeutic effect on acute and chronic hepatitis and metabolic toxic liver damage. Mainly manifested in: it can not only promote the formation of new liver cells by promoting protein synthesis, but also repair damaged liver cells.
      Its mechanism of action may be that silymarin enhances the production of glutathione in the liver, thereby helping to enhance its antioxidant capacity.
      Its strong antioxidant function can protect liver cells from free radical damage.
    2. On the other hand, silymarin has the effects of lowering blood lipids, blood pressure and blood sugar. It is also beneficial for preventing and treating cardiovascular and cerebrovascular diseases and improving immune function.
      In addition, more and more studies shows that silymarin has a good therapeutic effect in preventing and treating chronic diseases such as cardiovascular diseases, neurodegenerative diseases, and metabolic syndrome caused by oxidative stress.
    3. Anti-inflammatory and anti-fibrosis of Milk Thistle Extract Powder.

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