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Phellodendron Amurense Bark Extract

  • Assay: 10% ~ 98% Berberine Hydrochloride ( Berberine HCL )
  • Molecular formula: C20H18CLNO4•2H2O
  • Molecular weight: 407.85
  • CAS number: 633-65-8
  • Certification: ISO22000, Haccp, Halal
  • OEM ODM Available

    Feature

    Phellodendron Amurense is a commonly used Chinese medicine, and its dried bark is often used as medicine.
    Phellodendron Amurense Bark Extract mainly contains berberine, phellodendronine, jatrorrhizine, magnolamine, phellodendron lactone, phellodendronone, phellodendron acid, β-sitosterol, and campesterol.

    The dried bark of Phellodendtron chinense Schneid. contains berberine 4%-8%. The dried bark of Phellodendtron amurense Rupr. contains berberine 0.6%-2.5%. The dried rhizome of Coptis chinensis Franch. contains berberine 4%-10%.
    Berberine has a stable structure and exists in the form of quaternary ammonium salt. The extraction process of berberine is solvent extraction, and the active ingredients are extracted from the bark by immersion, percolation, reflux, etc.

    Specification-COA

    Test ItemsSpecifications
    AppearanceYellow Crystalline Powder
    Odor and TasteInodorous,extreme bitter
    IdentificationPositive reaction under test Procedures
    Assay≥98.0%
    Loss on Drying≤12.0 %
    Ignition Residue≤0.2%
    Other AlkaloidComply with the hygiene requirements
    Lead (Pb)≤1.0mg/kg
    Arsenic (As)≤1.0mg/kg
    Cadmium (Cd)≤1.0mg/kg
    Mercury (Hg)≤0.1mg/kg
    Total Aerobic Count≤1000cfu/g
    Yeast and Moulds≤100cfu/g
    E-ColiNegative
    SalmonellaNegative
    Staphylococcus AureusNegative

    Function and Application

    Phellodendron amurense extract has multiple pharmacological effects such as anti-inflammatory, antiviral, antibacterial, and hypoglycemic.

    1. Antibacterial effect. Phellodendron amurense extract has antibacterial effects on Staphylococcus aureus, Streptococcus, and Proteus.
    2. Both Phellodendron amurense water extract and alcohol extract have antioxidant effects. They can remove superoxide anion radicals and hydroxyl radicals produced in the hypoxanthine-xanthine oxidase reaction system.
    3. Berberine hydrochloride can relieve the symptoms of ulcerative colitis.
    4. Berberine is the main active ingredient in the anti-diabetic effect of Phellodendron amurense extract. This is because berberine and its metabolites can inhibit the production of glucose in the liver.
    5. Studies have shown that Phellodendron amurense water extract has a wide range of antiviral effects.

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