Salicylic acid is an organic acid that exists naturally in willow bark and can be metabolized from salicin. Salicylic Acid Powder is a white crystalline powder that is slightly soluble in cold water and easily soluble in hot water and ethanol.The molecular structure of salicylic acid contains a carboxyl group (-COOH) and a phenolic hydroxyl group (-OH). These two groups give it unique chemical properties.
| Reference Spec | BP2017/EP9.0/USP42 | ||
| Test items | Specifications | Test Results | |
| Characters | A white, or almost white , crystalline powder or white or colourless, acicular crystals, slightly soluble in water; freely soluble in ethanol (96 per cent), sparingly soluble in methylene chloride. | Complies | |
| Identification | A.158 °C -161 °C Melting pointl 58 °C to 161 °C | 158.6-160.5C | |
| B.The IR spectrum of sample complies with Salicylic acid CRS | Complies | ||
| Appearance of solution | Solution is clear and colourless | Clear | |
| Chlorides | ≤l00pptn NMTl00ppm | < l00ppm | |
| Sulfates | ≤200ppm NMT200ppm | <200ppm | |
| Heavy metals | ≤20ppm NMT20ppm | <20ppm | |
| Loss on drying | ≤0.5% | 0.02% | |
| Residue on ignition | ≤0.05% | 0.04% | |
| Related substances | 4-hydroxybenzoic acid | ≤0.1% | 0.001% |
| 4-hydroxyisophthalic acid | ≤0.05% | 0.002% | |
| Phenol | ≤0.02% | N.D | |
| Any other impurities | ≤0.05% | N.D | |
| Total impurities | ≤0.2% | 0.002% | |
| Assay ( on dried basis) | Contains C7H6O3 99.0%-100.5% | 99.6% | |
| Conclusion | Accordance with BP2017/EP9.0/USP42.The above items meet the requirement. | ||
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