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Thiamidol

  • Chemical Name: N-(4-(2,4-Dihydroxyphenyl)thiazol-2-yl)isobutyramide
  • CAS: 1428450-95-6
  • Molecular Formula: C13H14N2O3S
  • Molecular Weight: 278.33
  • OEM Available
  • Test Method: HPLC

    Feature

    Peptide Anmido was developed as a new functional cosmetic ingredient with a unique structure and biological activity. There are three processes for synthesizing Peptide Anmido. It is insoluble in water and oil, but soluble in alcohol.

    It has no cytotoxicity. As an efficient and safe whitening agent, it is widely used in whitening products and can also be used in experimental scientific research. When Peptide Anmido is used as a product formula, you need to pay attention to the formula and the feeling of use.

    Specification-COA

    ITEMSSPECIFICATIONSRESULT
    AppearanceOff-white to pale yellow crystallineOff-white crystalline
    SolubilityMeets the requirementsMeets the requirements
    IdentificationA. Infrared spectrum should conformComplies
    B. Should conformComplies
    Specific rotation+58°~+64°+61°
    Loss on drying≤3.0%2.3%
    PH4.5~6.55.0
    Moisture (water) content≤ 6.0%<4.6%
    Absorbance≤ 0.20%Complies
    Absorbance index360-390Complies
    Assay (calculated on the dried basis)≥95%99%
    Any individual impurity≤ 1.0%0.38%
    Sum of all impurities≤ 3.0%1.4%
    Bacterial endotoxins≤ 0.20 USP EU/mg<0.20 USP EU/mg
    SterilityMeets the requirementsMeets the requirements
    Conclusion:Product meets the requirements of USP36 

    Functions

    1. Whitening

    Peptide Amido has the effect of inhibiting melanin synthesis, which is very effective and can be effective at low concentrations.

    Its whitening principle is to interrupt the production chain of melanin and inhibit melanin directly from the source, thereby achieving whitening effect.

    The inhibition rate of human tyrosinase by peptide Amido is 119 times that of 377, 455 times that of kojic acid, and more than 3,000 times that of hydroquinone and arbutin.

    In creams, containing 0.1%~0.2% mass fraction of peptide Amido can significantly inhibit pigmentation.

    2. Freckle removal

    In a study on the efficacy of peptide Amidol on mild and moderate chloasma, it was found that after 12 weeks of using peptide Amidol, female patients with melasma had an improvement rate of more than 80% on both sides of their faces. Safe and effective treatment for melasma.

    Recipe suggestions:

    Peptideamide combined with hyaluronic acid is more effective and faster in treating chloasma. This is due to the benefits of hyaluronic acid on the skin barrier, which can help reduce the appearance of melasma.

    3.Potential uses

    Peptidemidol has potential uses in fertility protection and promotion, and has potential uses in male fertility protection and repair.

    Application

    As the core whitening ingredient used in cosmetics.

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